ORC ID , Onwukwe Chikezie Hart2 ORC ID , Chikezie Nkiru Ifeoma3 ORC ID , Nwagbara Chukwudi Thaddeus4 ORC ID , Offia Kalu5 ORC ID , Osuji Charles Ukachukwu5">
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ORIGINAL ARTICLE
Year : 2021  |  Volume : 3  |  Issue : 1  |  Page : 33-38

Patterns and Predictors of Left Ventricular Hypertrophy in Nigerians with chronic kidney disease


1 Department of Medicine, Cedarcrest Hospitals, Gudu, Abuja, Nigeria
2 Department of Medicine, Al Isawiya General Hospital, Directorate of Al Gurayat, Ministry of Health, Saudi Arabia
3 Department of Community Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria
4 Department of Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria
5 Department of Medicine, Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Awka, Nigeria

Correspondence Address:
Onwukwe Chikezie Hart
Al Isawiya General Hospital, Directorate of Al Gurayat, Ministry of Health
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ACCJ.ACCJ_41_20

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Background: Chronic kidney disease (CKD) impacts hugely on cardiovascular morbidity and mortality. Nigerian data on patterns and predictors of left ventricular hypertrophy (LVH) in persons living with CKD are scarce. The objective of the study is to describe the patterns and predictors of LVH in Nigerians with CKD. Methods: Recruitment and clinical assessment of adult Nigerians with CKD were done using standard procedures. Statistical analysis was done using appropriate statistical software. Results: Fifty-seven participants were involved in this study. Concentric and eccentric LVH occurred in 50% and 25% of the predialysis CKD patients, respectively, while 24% and 36% of the maintenance dialysis CKD patients had concentric and eccentric LVH, respectively. LVH patterns in dialysis-naive individuals were not significantly different from LVH patterns in persons on dialysis. The significant predictors of LVH in study participants were proteinuria, anemia, hypoalbuminemia, estimated glomerular filtration rate <30 mL/1.73 m2/min, and hypertensive nephrosclerosis. High calcium-phosphate product was a significant predictor of LVH in only participants on dialysis. Conclusion: This study showed no significant difference in LVH patterns among predialysis and maintenance dialysis CKD patients. Indices of deteriorating renal function were significant predictors of LVH in both categories of CKD patients. Early screening and treatment of significant risk factors of LVH are required in reducing CVD burden among CKD patients.


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